Half & Half (2002)

Half & Half follows two half-sisters, Mona and Dee Dee, who were raised separately but end up reconnecting and becoming roommates. Mona is the product of a one-night stand between her mother Phyllis and a rich white man, while Dee Dee is the result of Phyllis' marriage to a black man. The two sisters have very different personalities and get into comedic and heartwarming situations as they navigate their newly found sisterhood.