In a 19th-century rural village, a cursed man seeks revenge against those who wronged him. As the village becomes plagued by terrifying creatures and supernatural events, a pathologist and a vicar attempt to uncover the secrets behind the curse.
Seon-hwa is a new student at an elite medical school, and she is initiated into a dissection class headed by Dr. Han along with five other students, including her boyfriend Ki-beom. After the first class the students all start to share the same nightmare involving a one-eyed surgeon, and one by one they start to be murdered, the victims being discovered with their hearts removed. Seon-hwa and Ki-beom are convinced that these events are related to a beautiful cadaver with a rose tattoo on her breast, and they begin an investigation to uncover her identity.
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