Movies and TvShows featuring "rampaging-monster" theme.

When three different animals become infected with a dangerous pathogen, a primatologist and a geneticist team up to stop them from destroying Chicago. Athena-1, a research space station owned by gene manipulation company Energyne, is destroyed after Larry, a laboratory rat mutates and wreaks havoc. Dr. Kerry Atkins (Marley Shelton), the lone surviving crew member, is ordered to retrieve research canisters containing a pathogen by CEO Claire Wyden (Malin Åkerman) . Atkins is able to flee in the escape pod when the station imploded, but it disintegrates upon re-entry, killing her, and leaving a trail of debris across the United States, including the Everglades, where a canister is consumed by an American crocodile, and a forest in Wyoming, where a gray wolf is exposed to the pathogen. Primatologist Davis Okoye (Dwayne Johnson), a former US Army Special Forces soldier and member of an anti-poaching unit, works at a San Diego wildlife preserve. He befriends a rare albino gorilla named George, whom he saved from poachers. One night, one of the canisters crash-lands in George's habitat and George is exposed to it. George grows considerably larger and more aggressive over time. Davis is contacted by Dr. Kate Caldwell (Naomie Harris), a genetic engineer, who explains that the pathogen was developed by Energyne to rewrite genes on a massive scale. She had hoped to advance CRISPR research as a potential cure for disease but discovered that Energyne planned to use it as a biological weapon. The company fired her and got her sent to prison for attempting to expose them. George escapes from captivity and goes on a rampage at the preserve. Davis calms him down, but George is captured by a government team led by Agent Harvey Russell (Jeffrey Dean Morgan), and is put on an airplane. Meanwhile, Claire and her brother, Brett (Jake Lacy), send a squad of mercenaries led by Burke (Joe Manganiello) to capture the mutated wolf, Ralph, but they are all killed. Claire, hoping to capture Ralph and use George to kill Kate so they can cover up their plans, uses a massive transmitter atop the Willis Tower to lure the animals, who have been engineered to respond aggressively to a certain sound frequency, to Chicago. George reacts violently to the sound and crashes the plane. Davis, Kate, and Russell manage to parachute from the plane before it crashes. George, who survived the crash, joins Ralph as they make their way to Chicago. Davis and Kate convince Russell to help them steal a military medical helicopter, so they can get ahead of George. By the time they arrive, George and Ralph are attacking the city. The military are overwhelmed when the mutated crocodile, Lizzie, arrives, and causes more casualties. Davis and Kate attempt to steal a serum with the hope that they can turn the mutated animals back to normal. They are able to reach Energyne headquarters at the Willis Tower and steal a handful of serums, but they are spotted by Claire and Brett. Claire reveals that the serum only eliminates the animals' aggressiveness rather than revert them to their normal sizes, and she shoots Davis, though he survives. When George climbs up to the top of the tower and causes chaos, Claire orders Davis to distract him while she attempts to escape with Kate held hostage at gunpoint. During the escape, Kate slips the serum into Claire's handbag and pushes her towards George, who devours her alive, and thus the serum. George and the other animals destroy the transmitter, and consequently, the entire tower topples to the ground, which Davis and Kate survive by hovering in a damaged helicopter over the falling tower. With George returned to his normal personality, Davis stays to help him defeat the other two animals, while Kate flees to prevent the military from dropping a MOAB (Mother of All Bombs) bomb on the city. Russell is able to take a laptop of incriminating evidence from Brett, before Brett is crushed to death by falling rubble from the collapsing building. George and Davis trick Ralph into flying into Lizzie's jaws, which decapitates him, then George pierces Lizzie's eye with an iron bar, killing her. With the threat neutralized, the airstrike is aborted, and George helps in clearing the city of debris.

Urotsukidōji: Legend of the Overfiend is a controversial and shocking anime movie that tells the story of a realm where demons and humans coexist. A young student athlete named Nagumo is chosen to become the Overfiend, a powerful being destined to bring about the destruction and rebirth of the world. As Nagumo struggles with his newfound powers, he becomes caught in a violent and sexually explicit battle between demons, humans, and otherworldly creatures. With graphic scenes of violence, sexual assault, and extreme horror, Urotsukidōji: Legend of the Overfiend pushes the boundaries of conventional anime, making it a cult classic among fans of the genre.

A girl discovers a strange egg and unknowingly takes it to her village. It turns out the egg belongs to a monstrous creature. The lake monster emerges from the lake, wreaking havoc on the town and its people as it searches for the stolen egg.

When an unstoppable monster known as Doomsday threatens Metropolis, it's up to Superman to save the day. As the city crumbles under the force of Doomsday's rampage, Superman must summon all his strength and face the possibility of his own death in order to protect those he loves.

When Mechagodzilla returns to attack Tokyo, Godzilla must rise up once again to protect the city and its inhabitants. As the battle between the two giant creatures rages on, Tokyo finds itself caught in the crossfire of their epic clash.

When an earthquake awakens an enormous reptile known as Yongary, it starts rampaging through the city, causing destruction wherever it goes. A courageous astronaut and a team of scientists must find a way to stop the creature before it's too late.

Gorgo is a movie about a giant prehistoric creature that is captured and brought to London to be displayed as a spectacle. However, when the creature's mother comes looking for her baby, chaos ensues as the monsters wreak havoc on the city. It is up to a group of scientists and the Royal Navy to try and stop the rampage before it destroys everything in its path.

Reptilicus is a giant reptile that is awakened from hibernation in the ice by lightning storms in Lapland. The monster makes its way to Copenhagen, terrorizing the city and leaving a path of destruction in its wake. It's up to a group of scientists and military personnel to stop the rampaging creature before it kills everyone in its path.

A blazing fire rips its way through Bear Valley National Park. As the firefighters try to contain it, the animals are being forced out of their habitat including a beast that was better left undiscovered.

In the frozen north, a giant yeti is discovered frozen in ice. After being thawed, the creature escapes and goes on a rampage through Toronto. As the city tries to stop the monster, a young orphan girl forms a bond with the misunderstood creature.

After being exposed to radiation, a man grows into a giant with a disfigured face and goes on a rampage in Los Angeles. The authorities try to stop him, but their efforts are hindered by bureaucratic inaction and the monster's own tragic past.

A detective and his cowboy friend team up to stop a mad scientist who is stealing the bodies of murdered wrestlers, and bringing them back to life while electronically replacing their minds with those of animals to make them stronger and live longer. Posing as a successful masked wrestler, the cowboy quickly attracts the attention of the scientist and his henchmen as their next experimental subject...

A top secret government project seeks to harness sound as the ultimate weapon. But the power they unleash proves to be far beyond their control.