In the near future, the vast majority of humans are augmented with cybernetics, enhancing various traits like vision, strength, and intelligence. Mira Killian is a human saved from a crash and turned into a cyber-enhanced soldier. She joins Section 9, an anti-terrorist bureau, and works with her team to stop criminals. As Killian dives into the AI of a hacked geisha, she uncovers a mysterious hacker named Kuze. Killian's past is revealed to be a lie, and she seeks answers while evading her own organization's attempts to kill her. With the help of her team, Killian embraces her true identity and confronts those who deceived her.
In the near future, society is heavily reliant on cybernetic technology. Public Security Section 9, led by Major Motoko Kusanagi, investigates crimes related to cybernetics and deals with the challenges of rogue AIs, human enhancements, and political intrigue.
Ken Kariba, who was transferred to the Public Security Department of the Metropolitan Police Department, was investigating allegations of kidnapping of Japanese groups in Europe amid a series of explosions in various parts of Japan and the spread of fear of terrorist attacks with bombs. It eventually led to a series of terrorist attacks and, gradually, to a great conspiracy.
An explosion take place in a street of Tokyo. Many people were killed or seriously injured. One casualty is Chihiro, the wife of Public Security chief inspector Kuraki Naotake. While trying to find why his wife was being implicated in the explosion case, Kuraki comes into contact with Public Security sergeant Akeboshi Miki and Metropolitan Police Department inspector Osugi Ryota who are also investigating this case.
Inami and Tamaru work at the Public Security Mobile Investigation Unit Special Investigation Team, a team made up of specialists with different expertise. Inami tackles criminals with showy maneuvers, while Tamaru corners criminals with cool calculation. Together, the team tackles terrorists, new religious cults, military spies, secret narcotics organisations and complicit politicians.
Takano has been transferred to the Public Security Department, which is considered to be an elite among the Japanese police. A murder of a ruling party tycoon occurred near the scene of a bombing that occurred. An organ was removed from the body, and a balance with a heart and wings was left in the vicinity. Takano, who attended the scene of the bizarre incident, felt uncomfortable with the killing method that imitated ancient Egyptian mythology, and even though he began to tell the story, his colleague Himuro dismissed it.
Izumi Morikuchi, a county police officer, investigates a murder linked to a college student's tragic death and police misconduct. Driven by guilt and determination, Izumi uncovers dark truths and fights for justice.
High school student Saya Toma lost her parents and younger brother in an airplane accident. Detective Akio Kondo came and told her "your family has a high possibility that they were killed by people who have spec." That was the first time she heard of "spec". 6 years later, Saya Toma, who has never forgotten what the Detective said, decides to become a detective. She returns to Japan after receiving training by the FBI in the United States. Saya Toma is assigned to work unsolved cases in the Public Security Bureau. Meanwhile, because of Satoshi Chii's scheme, Juichi Ninomae considers Saya Toma his parents' enemy and tries to push her to the edge. Satoshi Chii's scheme has also caused Saya Toma and Juichi Ninomae to forget that they are brother and sister. The siblings are headed to a life-staking fight. A girl named Maho Ueno becomes involved in their fight. To protect Maho Ueno, Saya Toma uses "spec".
Set one year after the fight between detectives Saya Toma, Takeru Sebumi, and Satoshi Chii. More confrontations ensues between the detectives at the Unidentified Crimes Unit of the Tokyo Metropolitan Police Department. Takeru Sebumi returns after taking a break due to his eye problems. Kenzo Ichiyanagi is appointed section chief, while Kotaro Nonomura is demoted. New member Shu Kikkawa joins the team.
Saya Toma is a female detective with an IQ of 201. Takeru Sebumi is a career detective with a distinguished background. They work on cases by postulating the "SPEC" of the unknown criminals and then deduce the criminal's unknown "SPEC" to make arrests. A mystery occurs when bodies are found on a cruiser in the ocean. Saya Toma and Ryo Kase of the Tokyo Metropolitan Police Department are brought in to solve the case.
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