Mesa of Lost Women (1953) is a sci-fi horror film that takes place in the Mexican desert. The plot revolves around a mad scientist who creates a spider woman and a giant tarantula. The movie features elements such as crash landings, flare, erotic dance, narration, and a secret laboratory.
Paul, an American composer, arrives in the desert town of Real de Catorce where his father recently died. For the past ten years, Paul has been consumed with the task of composing an ending for the masterpiece of an early twentieth century musician. Being isolated from the world, he sees an opportunity to finish the symphony. However, Paul is caught up in a new mystery, the disappearance thirty years ago of a woman named Marianne.
In the American Southwest, a widower physician becomes stranded in a Mexican desert town after his car breaks down. He is held at gunpoint by an angry man who demands medical attention for his sick wife, who is in labor. With limited supplies and the threat of a sandstorm, the physician must perform an emergency caesarean section and find a way to escape the town before they all succumb to a deadly contagious disease.
Pablo, a shy teenager, meets Marco, who is a few years older than him. Together they go on a impromptu road trip to the Mexican desert, a trip that will make them face what they mean to each other. This experience will turn Pablo’s life around: his points of view, his strength and his own sexuality. Two guys and a video camera that will record their friendship, struggles and the possibility to find another destiny.
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