Fred Stevens is an aspiring songwriter from Schenectady who journeys to New York City, hoping to make a name for himself. On the train he meets dental assistant Edna Baker, and the two embark upon a friendship that evolves into her falling for him. While struggling in Tin Pan Alley, Fred falls in with his composer partner's gold-digging sister-in-law Eileen. Eileen really becomes interested when she finds out Fred is carrying his life savings.
Mary Lynde (Theda Bara) is an innocent girl who has grown up in New York's Greenwich Village. One of the artists there, Felix Benavente (Sidney Mason), uses her as model when he paints a portrait of the Madonna for a church. His friend Robert Sinclair (Hugh Thompson) corrupts Mary so that her father (Walter Law) casts her from his home. She goes to live with Sinclair in his mountain lodge, but after the birth of a child, he callously casts her aside. Subsequently, her baby dies and she sinks to the depths of despair.
A small-town, jazz-mad girl, Peggy Marston (Dorothy Revier), becomes involved with a pair of society thieves, Maurice Dumond (Armand Kalis) and Maxine (Mildred Harris), and finds herself falsely accused of possession of stolen jewels.
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