Hande and Ceren who are about to graduate from college, are close friends since childhood. Ceren is a spoiled daughter of a wealthy family and Hande is a daughter of manicurist Nermin.

Kaybolan Yıllar is a Turkish TV show about a group of friends who get separated during their childhood due to unforeseen circumstances. The show follows their individual lives and struggles as they grow up, only to reunite many years later. It explores themes of friendship, love, and the impact of past experiences on the present.