The story of Kariya 2 revolves around Kariya, a small-time local goon who is employed by an influential underworld don. All is well with Kariya until he falls in love with Janaki, which leads to several unfortunate events that change their life completely.

The story is set on the backdrop of Gopinatham village where Kempa (Santosh) is living with his sister Pragna (Nayana) and his life changes when the STF forces who arrive there in the search for Veerappan end up killing her. Kempa is out to seek revenge and in no time kills the three STF guys who did it

Ganapa is based on an incident in Bengaluru's underworld. The film takes a realistic approach, not on rowdyism, but on people affected by it.