Round the Moons Between Earth and Sea is a dramatic movie set in 1970s Naples, Italy. The story revolves around a dysfunctional family that experiences tragic events such as the loss of their father and mother, murder, and martyrdom. The plot also includes elements of prophecy, the reign of Roman Emperor Nero, an earthquake, and the relocation of the family. Through a nonlinear timeline and montages, the movie delves into the themes of Christianity and the struggles faced by the characters in southern Italy.