LouisLouise is a Flemish soap opera based on the Argentine success Lalola format and has been broadcast since 24 September 2008 on vtm. It is the successor of the series Sara.

A former hairdresser graduates from law school and starts working as a cheap legal consultant. Her ambition, her spontaneous and unique way to investigate cases, her big heart and her first successes as a lawyer soon deliver her many clients.

Straight-talking Superintendent Liese Meerhout leads the homicide department in the Antwerp police force. She and her team go to great lengths to ensure justice is served, even if it means they too cross the line between right and wrong.

A succesfull busninessman who has it all is looking for a new challenge and decides to hire a contract killer to assassinate him.