"My heart is ice, my passion consuming fire. Let men beware," exclaimed Theda Bara (via an inter-title, of course) in this "Vamp" melodrama based on Grabriele D'Annunzio's 1898 story La Gioconda.

Eleanor Leavenworth (Seena Owen) is about to be arrested for the murder of her rich bachelor uncle, and suspicion is cast on each member of the Leavenworth household until Raymond (Bradley Barker), an attorney in love with Eleanor, solves the mystery and produces the culprit, who confesses and falls to his death while trying to escape.

Denise Fleury supports her invalid mother in the Montmartre slums by making artificial flowers in a factory. When she loses her job, Denise is convinced by her friend Suzanne to join her working in a cabaret.

Wealthy Clytie Rogers writes a novel in which a society girl commits a burglary, but it is "roasted" by critic Jimmy Gilpin, who writes that her story is completely implausible. To prove him wrong, Clytie decides to feign a robbery and enters an apartment through an open window. She is apprehended by a policeman, who mistakes her for local robber "Powder Nose Annie." Gilpin sees her in jail and, posing as crook Jimmy of the Dives, arranges to break her out and take her on a robbing spree. Finally, Jimmy returns her to her parents and then calls at her home as Gilpin, the critic. Clytie is suprised but forgives the deception and agrees to marry him.

Kate Tarleton grows up on a Southern plantation and becomes engaged to her guardian, Dr. Robert Manning, a famous surgeon. When Robert, Kate, and her younger sister Mary Lou visit New York, where the doctor wishes to conduct medical experiments, the superstitious Kate goes to the home of a fortune-teller named Stella Hill. Stella, whose principal business is white slave trafficking, drugs Kate and forces her to work in a "den of vice," run by Stella and her accomplice Jimmy Bristol, where she contracts syphilis and goes insane. Robert, Detective Ellis, and a lawyer named Billy Meredith rescue Kate, who recovers her sanity but remembers nothing of her bondage.

This silent drama's story is based on the Broadway play Hail and Farewell by William Hurlbut.

Jaffery Chayne is the spectacular one of four chums, the others being Hilary Freeth, a literary man, Adrian Boldero, a short story writer, and Tom Castleton, a playwright. The story opens with Tom Castleton going on a voyage for his health and leaving with his friend, Adrian, the manuscript of the first novel he ever attempted. Shortly after Castleton's trip, he dies at sea and when word is received by Adrian of his friend's death, the temptation to secure the girl he loves by publishing his friend's novel and taking the money and credit from it is so strong that he succumbs and becomes the "literary lion of the hour."

Bob Stafford, the wastrel son of a wealthy businessman, is disowned by his father for his reckless and irresponsible ways. He changes his name and opens a gym for wealthy young girls, hoping to land a rich and pretty wife. He meets and falls for pretty young Eileen, but a rival soon drives him out of the gym business. He gets a job in an airplane factory owned by Eileen's father, who is soon told by a rival that Bob is really out to steal a new airplane invention so he can give it to his father.

In San Juan, Puerto Rico, The Drifter, young and educated, and The Seeker, old and feeble-minded, meet and form a partnership. The Seeker meets Rosario, unaware that she is his daughter, left there 20 years previously when his mind was affected by a tropical storm that killed his wife and wrecked his home. Rosario is deeded land belonging to her father and is about to sell it to Clifford Fayne when The Seeker discovers gold there and urges her to desist. Fayne lures her to a cabin and tries to force her to sign the bill of sale; The Drifter and her father rescue her; the father is mortally wounded but lives long enough to learn that Rosario is his daughter and that she will be happy with The Drifter.

Madge Kennedy stars as a young woman of modest means, posing as a millionairess in order to attend a hoity-toity society ball, where she hopes to snare a rich husband. Here she meets handsome young Tom Moore, who is likewise impersonating a man of wealth.