Trade tells the story of two men, one a streetwise hustler, the other a straight-laced lawyer, who meet and form a relationship that brings to light who they really are. Inspired by the book "Boulevard Girls" by David Kaye.

Wishing to dispose of his wife, psychiatrist Dr. Elliott makes his patient Nina think that she suffers from a compulsion to kill. He drugs Nina, murders his wife and leaves evidence that points to Nina. The latter, pre-conditioned by Elliott, also thinks she is guilty.