Yumi's Cells follows the life of Yumi, a game developer working at an office. The show explores her personal growth, friendship, and romantic relationships, all depicted through the inner workings of her brain cells. It combines live-action and animation to present a unique and humorous perspective of a career woman's life.

Jang Deuk-Cheon is the chief of a crime squad. At home, he is kind and friendly father to his daughter. He meets a human clone and gets involved in a shocking case. A battle takes place between human clones.