A man defends a beleaguered rural community from murderous drug-traffickers.

Waltair Veerayya, a fisherman turned smuggler, is approached by suspended police officer CI Seethapathi to extradite a notorious drug lord from Malaysia to India in exchange for money. Veerayya accepts the deal and forms a plan with his friends. However, things take unexpected turns as Veerayya encounters Dr. Nithya and her daughter and Seethapathi's brother-in-law gets caught by the drug lord. Veerayya saves the day and exposes the drug lord's true intentions. In a twist of events, Veerayya reveals his ultimate target, kills the drug lord, and fulfills his brother's last wish of avenging the deaths caused by the drug syndicate.

Pantham is a movie about a vigilante who fights against corrupt politicians to bring justice to society. With action-packed sequences and intense drama, the movie showcases the struggle of the protagonist in his quest for righteousness.