Sebastián Silva, a depressed and ketamine-addicted artist, meets social media influencer Jordan Firstman at a nudist beach. They discuss collaborating, but Sebastián accidentally falls to his death. His housekeeper, Vero, hides his body and a series of events unfold, revealing the truth.

Crystal Fairy & the Magical Cactus is a movie about a group of friends traveling through Chile's Atacama Desert in search of a hallucinogenic cactus. Along the way, they encounter various misadventures and personal revelations.