Respected banker Karel Brand is seen as a marketable emblem of probity. When he loses 350,000 guilders, his reputation is tarnished – without the respect attached to it, he loses his job. Brand becomes unemployable, and his creditors suddenly start calling in their debts. His young daughter Willy suffers the same fate.

An independent-thinking doctor in a rural community with his own ideas of how medicine should be practiced begins to find himself ostracized from the community after one of his patients commits suicide.

Mientje comes from an ordinary working class family. Her father's alcoholism threatens to put an end to her engagement to Herman, her well to do fiancée. When her parents divorce, Mientje comes into conflict with her future mother-in-law. A grim but ultimately hopeful look at marital problems, poverty, lost love and alcoholism in a working class neighbourhood in Amsterdam.