The film “A House On 41st Street”, tells the story of a family who are struggling with a happening and the consequences after. Something happens that results to a conflict between two brothers, following by some unpleasant incidents between the daughter-in-law and Mother of the family.

Elham goes to the doctor because of strange headaches she has recently. But finds that she has a tumor in her brain and she may be gets amnesia if has a surgery. Now she has to do a difficult choice.

Bahar has divorced her husband and is now remarried living a new life. Her son from her previous marriage, Payam, has leukemia and now she must find her ex-husband in order to save her son no matter what it takes.