Novo Mundo is a historical drama TV show set in Brazil during the 18th century. It tells the story of Anna Millman, a young Austrian woman who embarks on a journey to Brazil when she agrees to marry a Portuguese emperor. Along the way, she faces challenges such as fake deaths, prejudice, and a love triangle.

Seven friends who met in their youth at an English course meet again 25 years later; Lara, Taís, Helena, Adriana, Renée, Natália and Carol, each of them has a different personality and origin, but they share a deep affection.

In 1856, the emperor Dom Pedro II lived a marriage of appearances with Teresa Cristina, with whom he was forced to marry at a young age by his parents' political alliance, having two daughters with her: Isabel and Leopoldina. He truly loves Countess Luisa, a cultured and time-ahead woman who fights for the abolitionist cause and women's rights, married to Eugenio, the emperor's cousin. At the same time there are sisters Pilar and Dolores: the first went to a convent after her mother's death in childhood, growing up among books and dreaming of studying medicine - inspired by the story of Elizabeth Blackwell, the first doctor in the world -, while the second stayed at home to take care of her father, Colonel Eudoro, growing up repressed, illiterate and without vanity.

Three couples meet in the middle of Carnival, trying to get together in the midst of various conflicts that have the biggest party in Brazil as a scenario - and often as a cause.