Dr. Filatov, a first—class gynecologist, a favorite of women, but at the same time a faithful family man, is suddenly abandoned by his wife. Trying to fill the void created by her departure, Filatov begins to look for a new love. But the more he gets to know the woman, the more he realizes that his wife is absolutely perfect and she must be returned at all costs.

A wealthy and influential family hires Katya as a nurse for a dying father. Most unexpectedly, the young woman becomes his closest confidant and the only person in his life whom he can trust. Passions run high around Katya as a huge inheritance is at stake. From a modest nurse, whose only task was to care for the sick in the last days of his life, Katya involuntarily turns into an active participant of the family drama with all its hopes, fights and disillusions. It turns out that the seemingly happy and tight-knit family has its skeletons in the closet, and these secrets can come at a price of a human life.

The main characters are five young girls who follow each other's lives on a social network. Veronica suffers from complexes due to excess weight, Ira is looking for true love, Olya is going through a crisis in family relations, Alyona is focused on creative realization, which is hindered by her husband, Dasha selflessly helps others, forgetting about herself. The desire to make their lives better leads them to the online marathon "Happiness is you!", which was launched by the psychology guru. But happiness is individual for each person, and universal advice does not always work.

The story begins in the spring of 1989, in the provincial town of Kasimov. Nina Golubeva graduates from school with a medal and dreams of becoming a fashion designer. The first serious love turns into a difficult ordeal – the guy leaves the girl pregnant. At the beginning of the "dashing 90s" Nina moves to inhospitable Moscow and learns to rely only on herself. She will have both recognition and success ahead of her, but happiness and true love will have to go a difficult way.

Sasha, 30, is a serial loser trying his best to become a successful business coach. Fate leads him to billionaire Oleg Kalugin, who decides to hire a cheerful dreamer as a coach. However, Kalugin does not need business advice, in which the guy knows nothing, but the secret of his ability to sincerely enjoy life despite poverty and other problems. From this moment on, drastic changes begin in Sasha's life, which show the real price of success. Step by step, he is moving further away from happiness, plunging into a world of deception, betrayal, hatred and really big, but dirty money.

When medical colleagues determine that an operation for a hopeless patient is incompatible with life, a young shift attendant tries to save him even at the cost of her work.