Bill and Jo Harding, advanced storm chasers on the brink of divorce, must join together to create an advanced weather alert system by putting themselves in the cross-hairs of extremely violent tornadoes. In their journey, they face personal struggles and rival storm chasers, while trying to prevent a disaster similar to the one that happened to Jo's family. Through their courage and determination, they manage to overcome obstacles and ultimately reconcile their relationship.

As storm season intensifies, the paths of former storm chaser Kate Carter and reckless social-media superstar Tyler Owens collide when terrifying phenomena never seen before are unleashed. The pair and their competing teams find themselves squarely in the paths of multiple storm systems converging over central Oklahoma in the fight of their lives.