Russian Dolls follows the lives of several characters as they navigate the complexities of dating and romance in the fast-paced and unpredictable world of modern relationships. The story revolves around a group of friends, their love lives, and their search for happiness. It explores themes of love, friendship, and self-discovery.

Xavier is a 40-year-old father of two who relocates to New York City after his wife moves with their children. He encounters various challenges, including dealing with his ex-wife's new relationship, navigating Chinatown as an immigrant, and exploring new romantic opportunities.

A young French student moves to Barcelona for an exchange program and moves into a chaotic apartment with other international students. As they navigate different cultures and languages, they form friendships and romantic relationships. The group experiences the ups and downs of love, lust, and the challenges of living in a foreign country.