In the sequel to Hell Comes to Frogtown, the Mutant-Frog leader of Frogtown kidnaps a professor and forces him to make a serum that will turn everyone into Frogs, they also kidnap some people to test the serum on. And courageous Sam Hell will have to save them.

Scott Shaw stars as the lone samurai, MAX HELL, on the trail of the serum which was unleashed to turn all of humanity into Toads.

This film follows the lead character, Max Hell, who goes on a mission to rescue Dr. Trixi T from the clutches of the evil Mickey O'Malley.

In a post-apocalyptic wasteland, a fertile man named Sam Hell is chosen by the government to rescue a group of women who have been abducted by mutant frogs. Equipped with a chastity belt that can only be removed by the right woman, Sam embarks on a dangerous and hilarious journey to save the women and ensure the survival of humanity. Along the way, he faces various challenges, encounters bizarre characters, and battles against the mutant frog army. With his trusty colt revolver and the help of a skilled warrior named Spangle, Sam fights to fulfill his mission and bring hope to a desolate world.