The Duke boys and their cousin Daisy head to Hollywood to sell some musical recordings in order to raise money to build a new hospital in Hazzard County. They soon find themselves in the middle of a plot to steal the valuable recordings and must use their famous car, the General Lee, to outwit the bad guys and save the day.

The Dukes of Hazzard: Reunion! is a movie set in the American South, featuring action, adventure, and TV movie elements.