An experimental drug designed to repair brain damage gives a chimpanzee advanced intelligence. When the chimp starts an uprising, a scientist must decide where his loyalties lie.

Several generations following Caesar's reign, apes – now the dominant species – live harmoniously while humans have been reduced to living in the shadows. As a new tyrannical ape leader builds his empire, one young ape undertakes a harrowing journey that will cause him to question all he's known about the past and to make choices that will define a future for apes and humans alike.

In this sequel to 'Rise of the Planet of the Apes', a decade after the ALZ-113 virus outbreak, humans are dying off while apes thrive. Caesar, the chimp leader, must confront mistrust and betrayal as both tribes vie for control. The fate of the Earth hangs in the balance.

After the ALZ-113 virus wipes out billions, intelligent apes led by Caesar face an all-out war against a ruthless military faction led by the Special Forces Colonel. In his quest for revenge, Caesar must confront his own darker instincts.