Ten years after the Battle of the Breach, Jake Pentecost, son of Stacker Pentecost, becomes a Jaeger dealer. He is forced to join the Pan-Pacific Defense Corps and train new Jaeger cadets after encountering the orphan girl Amara. Together, they must fight against a rogue Jaeger, the drones controlled by Kaiju brains, and a Mega-Kaiju heading towards Mt. Fuji. In the end, they succeed in stopping the Kaiju and vow to be ready for their return.

In the near future, Earth is attacked by monstrous sea creatures known as Kaijus. To combat them, humanoid fighting machines called Jaegers are created. As the Kaijus evolve and the Jaegers become less effective, Earth's governments lose faith in the program. In a desperate effort to save humanity, a former pilot and a trainee are paired up to drive a seemingly obsolete Jaeger and stop the apocalypse. Meanwhile, a scientist discovers the true nature of the Kaijus and seeks to control their invasion. The Jaeger forces assemble to destroy the portal and end the war.