Clark Griswold, a food processing salesman, decides to take his family on a cross-country road trip to the Walley World theme park. Along the way, they encounter numerous obstacles and misadventures, including getting lost, having their car vandalized, and dealing with the eccentricities of relatives they visit. Despite all the challenges, Clark is determined to reach their destination and give his family the vacation they deserve.

When the Griswold family wins a trip to Las Vegas, they experience hilarious misadventures involving gambling, showgirls, and family chaos.

The Griswold family's plans for a big family Christmas predictably turn into a big disaster. Clark sets out to have the perfect Griswold family Christmas, but his well-intentioned efforts only result in chaos and mishaps. From accidentally cutting off and taunting truck drivers on the road, to sticking to everything he touches due to excess sap, Clark's comedic attempts at creating the ideal holiday experience fall flat. As the family faces a series of misadventures, including failed attempts at setting up lights and a disastrous Christmas Eve dinner, Clark's determination to salvage the holiday leads to unexpected results. With the arrival of his unpredictable cousin Eddie and an explosive finale involving a radioactive Santa, the Griswold family's Christmas will certainly be one they'll never forget.

The Griswold family embarks on a trip to Europe, encountering various mishaps and comedic adventures along the way. From awkward encounters with foreign cultures to unexpected encounters with romantic interests, their vacation quickly turns into a hilarious chaos.