In 'My Friend Irma Goes West', Irma and her friends head to Hollywood where they find themselves in various comedic situations. Along the way, they encounter gangsters, con men, and even a chimpanzee. Will they be able to navigate the crazy world of show business and achieve their dreams?

My Friend Irma follows the hilarious misadventures of a group of friends as they navigate through misunderstandings, romantic rivalries, and comedic chaos. The story revolves around Irma, a beautiful but naive blonde who unwittingly gets tangled up in a web of deception and shenanigans. With her loyal friends by her side, including her witty roommate Jane and the bumbling but lovable musician Al, Irma faces a series of hilarious situations that test their friendships and lead to unexpected outcomes.