In 'My Big Fat Greek Wedding 2,' the Portokalos family is back for another wedding, but this time it's Toula's parents who are getting remarried. As they plan for the big day, they face a series of comedic events and family dramas, all while trying to navigate their Greek heritage and American culture.

A young Greek woman named Toula falls in love with Ian, a non-Greek, and faces the challenge of convincing her family to accept him. As she comes to terms with her heritage and cultural identity, Toula navigates the complexities of love, family, and belonging in a heartwarming and comedic way.

Following the passing of their patriarch, Toula embarks on a journey to Greece in search of her father's childhood friends, aiming to bring them together for a family reunion.