The battle lines have been drawn, placing old friends Kira and Athrun on opposing sides in the war. The resulting battle will mark a turning point in their lives as Athrun and the Zaft forces launches a major offensive designed to end the war once and for all!

The economic gap widens between the affluent, technologically advanced, hybrid Coordinators and the simple Earth Alliance known as the Naturals; the rift, unsurprisingly, has driven them apart in the 70th year of the Cosmic times. In an effort to bridge the chasm between them and the Coordinators, the Naturals have built five Gundam warriors that they hope will serve as their potent weapons. But will their plan work?

The Earth Forces has commissioned another Archangel-class ship, the Dominion; its sole mission is to destroy the renegade Archangel. As the battle draws to its ultimate conclusion, it is possible that humanity itself will be the victim. Kira, Athrun, and the others must stop a war that threatens both sides with genocide!