Greg Focker, a male nurse, falls in love with Pam and wants to impress her father, Jack. Over a hectic weekend at her parents' house, Greg must use his skills to charm his way out of trouble. But Jack has a talent for finding the truth, and Greg has been hiding some things. Will he ever gain Jack's approval, and is love truly blind?

Greg Focker, a male nurse, is appointed as the new head of the family by his father-in-law after a secret heart attack. However, when Greg considers becoming the spokesperson for a male enhancement drug, his father-in-law suspects him of having an affair. Chaos ensues as Greg tries to prove his innocence while dealing with family drama and planning a birthday party for his twins.

In this sequel to 'Meet the Parents,' Gaylord Greg Focker (Ben Stiller) invites his fiancée's parents, ex-CIA agent Jack Byrnes and his wife Dina (Robert DeNiro and Blythe Danner), to meet his parents. However, Jack discovers that the Fockers are very strange. With a hippie and retired lawyer dad, and an open sex therapist mom, Jack begins to question if this is the right family for his daughter to marry into. As the two families try to become one, chaos ensues.