In a world plunged into chaos, the battle for humanity's future begins. As the antichrist rises to power, a group of determined individuals takes a stand against the forces of evil.

Left Behind II: Tribulation Force follows a group of believers who come together to resist the Antichrist and his rise to power during the end times. As natural disasters and famine plague the world, the born-again Christians must navigate a dystopian society while staying true to their faith. With violence, love interests, and religious conversions, they face the challenges of a post-rapture world.

After the Rapture, an investigative journalist looks into the effects of the event, including a one-world government and the rise of a charismatic politician. Chaos ensues as she uncovers the truth and confronts the challenges of faith and survival.