When Jimmy's invention goes wrong, he ends up in Timmy Turner's world. Together, they must find a way to fix the mess and save both of their dimensions from disaster. Along the way, they encounter mistaken identities, mad scientists, and a love triangle.

When Jimmy Neutron and Timmy Turner accidentally switch dimensions, they must work together to find a way back home while trying to defeat an evil villain.

In Jimmy Timmy Power Hour 3: The Jerkinators!, Jimmy Neutron and Timmy Turner discover that their dimensions are merging and they must work together to stop the evil villain, Professor Calamitous, from taking over both worlds. Along the way, they encounter various challenges and hilarious situations as they use their intelligence and problem-solving skills to save the day.