Dracula and his family embark on a luxury cruise for monsters, but Dracula falls in love with the ship's captain, Ericka, who is hiding a dangerous secret. As chaos ensues, Dracula and his friends must save the day and ensure all the monsters have a memorable vacation.

After an experiment gone wrong, Drac and his friends are transformed into humans. They must team up and race against time to find a cure and switch back before it becomes permanent.

Dracula is worried about Mavis leaving the hotel, so he tries to bring out the monster in his half-human, half-vampire grandson. However, when Dennis' fifth birthday approaches, Dracula becomes desperate to make his grandson a vampire. Meanwhile, Mavis considers moving to California to raise her son around humans. As tensions rise and chaos ensues, Dennis finally manifests his vampire powers, leading to a battle against a group of demons. In the end, Dracula and Mavis decide to continue raising Dennis at the hotel.

Dracula, the owner of Hotel Transylvania, operates a high-end resort where monsters can be safe. When a human named Jonathan discovers the resort, Dracula goes into overprotective mode to keep his daughter Mavis safe from a potential human threat. However, as Jonathan charms everyone at the hotel, including Mavis, Dracula realizes that he has broken Mavis' heart by manipulating her and must find a way to make things right.