Walking Vengeance follows the story of a strong female character seeking revenge against a drug baron with the help of her female gang. As they navigate through the dangerous world of organized crime, they face numerous obstacles and form unexpected alliances.

A prostitute named Isabel dreams of leaving her dangerous life in the streets of Madrid. She forms a bond with a gangster and drug mule named Miguel. Together, they plan to start a new life away from the crime and violence that surrounds them. However, their plans are threatened when Isabel's past catches up with her, forcing them to confront their own demons and make difficult choices.