In a war-torn world, two brothers, Edward and Alphonse Elric, risk everything to find each other. After attempting forbidden alchemy to resurrect their mother, Edward loses an arm and a leg while Alphonse loses his entire body. Determined to restore their bodies, they embark on a journey to find the Philosopher's Stone. Along the way, they uncover a secret society, encounter Nazis, and face the wrath of a powerful alchemist.

In this action-packed anime film, the brothers Edward and Alphonse Elric find themselves embroiled in a new adventure when they travel to the remote city of Milos. There, they encounter a group of rebels fighting against the oppressive government, as well as uncover a deep secret of the alchemy world. As they navigate through dangerous conflicts and face powerful adversaries, the brothers must uncover the truth behind the Sacred Star of Milos.