Fly me to the Saitama is a hilarious comedy movie that takes place in Saitama, Japan. It follows the story of a Tokyo resident who faces discrimination and prejudice when he moves to Saitama. Through humorous and entertaining situations, the movie explores themes of class warfare and cultural differences.

People of Saitama Prefecture, who have been persecuted by Tokyoites for a long time, stand up for their freedom. Thanks to Momomi Hakuhodo (Fumi Nikaido) and the Saitama Liberation Front, laissez-passer is abolished. The people of Saitama Prefecture can once again enjoy their peaceful daily lives, but the Saitama Liberation Front heads toward its next goal. This leads to a big case.