In the year 2050, the government organizes a car race where the objective is to kill as many competitors as possible. The race takes place in a world overpopulated and controlled by corporations. Death, mayhem, and murder are constant in this grindhouse-style competition, filled with black humor and political satire. As the race progresses, a female spy and femme fatale navigate the dangerous landscape while a child in a wheelchair is in jeopardy. With voyeurism, passionate kisses, and provocative scenes, Death Race 2050 offers a thrill ride like no other.

In a dystopian future, the United States is ruled by a dictator, and the most popular sport is a deadly cross-country race where racers score points by killing pedestrians. Frankenstein, the reigning champion, is targeted by resistance fighters and must navigate dangerous obstacles to win.