The Grim Reaper teams up with the Kids Next Door to stop an evil plot by a Jamaican villain. They must use their spy skills and gadgets to save the world from destruction.

Codename: Kids Next Door - Operation Z.E.R.O. follows a secret organization of children who must save the world from an evil plot. As they face danger, they learn the importance of teamwork and friendship. With the fate of the world at stake, they embark on a mission filled with action, adventure, and comedy.