In 'Babysitting 2,' a group of friends travels to Brazil for a vacation. During their trip, they find themselves in the middle of the jungle and encounter various obstacles and dangerous situations. They must navigate through a hostile tribe, spider bites, trapped situations, and falling from heights. The plot also includes comedic elements and explores themes of friendship and adventure.
When a group of friends host a wild party, their babysitter suddenly cancels and they are left to care for a mischievous child. Chaos ensues as they navigate through humorous and unexpected situations.